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Comparison of the in vitro growth properties of wild-type HSV-1(F) and the recombinant viruses YK304 and YK311. Vero cells were infected with HSV-1(F) (circles), YK304 (squares), or YK311 (triangles) at a multiplicity of 10 (A) or 0.01 (B) PFU per cell. Supernatant and cells were harvested at the indicated time points, and titrations of cell lysates were performed on Vero cells.
