FIG. 1.

Schematic diagram of the two recombinant VSVs used in this study. (A) VSVΔG*-EbolaGP is a VSV pseudotyped with Ebola virus GP that contains the GFP-encoding gene instead of the VSV G protein-encoding gene and thus is not infectious unless a receptor binding/fusion protein (e.g., Ebola virus GP) is provided in trans. (B) Chimeric VSV-EbolaGP contains the Ebola virus GP-encoding gene in place of the VSV G protein-encoding gene and therefore can undergo multiple cycles of replication without complementation.