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Neutralizing activity of MAbs to Zaire GP. VSV pseudotyped with GP of Ebola virus species Zaire or authentic Ebola virus species Zaire was incubated with purified antibodies (10 μg/ml) and inoculated onto 293 cells. Infectivity was determined by counting fluorescent cells. The relative percentage of infectivity was determined by setting the number of infected cells in the presence of normal mouse ascites (approximately 50 to 100 GFP-positive cells per microscopic field) at 100.
