FIG. 2.
Neutralization of luciferase reporter viruses. (A) Neutralization by MAbs against the CD4 binding site (CD4bs), CD4 induced site (CD4i), and the V3 loop (anti-V3 loop). (B) Neutralization by sera isolated from a macaque infected with SHIVSF162 (serum 26419-32) and SHIVSF162P3 (serum 353-66N). Percent neutralization was determined by luciferase expression by viruses infected in the presence relative to the absence of antibodies. Three independent assays were carried out and representative neutralization curves are shown.