TABLE 2.
Humoral immune response in SHIVSF162PC i.v. and IVAG infected animals
| Animal no. | Protein | Reactivity with strip in immunoblot assaya
|
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| i.v. infected animals
|
IVAG infected animals
|
||||||||||||||||
| w2 | w4 | w7 | w9 | w12 | w19 | w24 | w33 | w3 | w4 | w5 | w6 | w8 | w12 | w16 | w20 | ||
| CB79 | gp120 | − | − | + | ++ | +++ | +++ | ++++ | ++++ | ||||||||
| gp41 | ± | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | |||||||||
| p31 | − | + | ++ | ++ | ++ | ++++ | ++++ | ++++ | |||||||||
| p27 | − | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | |||||||||
| T027 | gp120 | − | − | − | − | ± | +++ | +++ | +++ | ||||||||
| gp41 | − | +++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | |||||||||
| p31 | − | − | − | ± | ± | ± | ± | ± | |||||||||
| p27 | − | +++ | +++ | +++ | +++ | +++ | +++ | +++ | |||||||||
| AV45 | gp120 | − | − | − | − | − | − | − | − | ||||||||
| gp41 | − | − | − | − | − | − | − | − | |||||||||
| p31 | − | − | − | − | − | − | − | − | |||||||||
| p27 | − | − | − | ± | ± | ± | ± | ± | |||||||||
| BD19 | gp120 | − | − | − | − | − | − | − | − | ||||||||
| gp41 | − | ± | +++ | +++ | +++ | ++++ | ++++ | ++++ | |||||||||
| p31 | − | − | − | − | − | − | − | − | |||||||||
| p27 | − | − | − | ± | ± | ++++ | +++ | ++++ | |||||||||
| BE72 | gp120 | − | − | − | − | − | − | − | − | ||||||||
| gp41 | − | + | +++ | +++ | +++ | +++ | ++++ | ++++ | |||||||||
| p31 | − | − | − | − | − | − | − | − | |||||||||
| p27 | − | ++ | +++ | ++ | ++ | +++ | +++ | +++ | |||||||||
a
Reactivity was determined by comparison with two internal IgG strip controls. Scoring, relative to level I and II control bands, was as follows: −, an absent band; ±, intensity lower than the level I band; +, intensity equal to the level I band; ++, greater than the level I but less than the level II band; +++, intensity equal to the level II band; ++++, greater than the level II band.