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Binding of IgG to immobilized influenza A virus. Initially approximately 4,000 resonance units (RU) of biotinylated virus (bPR8) were bound to SA sensor chips coated with SA in a series of injections (not shown). This was taken as the baseline position. Various concentrations of MAb H36 (a) and MAb H37 (b) (as indicated, in micrograms per milliliter) were injected (arrowhead) and were allowed to flow over and attach to virus. Sensorgrams of the binding of MAbs in real time are shown.
