FIG. 2.

Chromosomal location of eight novel CISs identified by SNP-based mapping. CIS loci were mapped by monitoring the inheritance of SNPs, or insertion-deletion polymorphisms, in the Frederick IBMP mice (Fig. 1). The number of recombinant N₂ animals over the total number of N₂ animals typed for each polymorphism is shown to the left of the chromosome maps between each pair of loci. The recombination frequencies, expressed as genetic distance in centimorgans (±1 standard deviation), are also shown. The upper 95% confidence limit of the recombination distance is given in parentheses when no recombinants were found between loci. When recombination between genes was observed, gene order was determined by minimizing the number of recombination events required to explain the allele distribution pattern. The positions of loci on human chromosomes, where known, are shown to the right of the chromosome maps. References for the map positions of human loci can be obtained from LocusLink (http://www.ncbi.nlm.gov/LocusLink).