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. 2003 Feb;77(3):2046–2055. doi: 10.1128/JVI.77.3.2046-2055.2003

FIG. 7.

FIG. 7.

Avidity of the anti-Env IgG raised by the IIIB Env-DNA vaccines. Sera were analyzed from week 20 in an Env-specific NaSCN-displacement ELISA. Plates were coated with recombinant gp120IIIB. Sera were collected from sgp120IIIB-DNA (▪), sgp120IIIB-mC3d1-DNA (○), sgp120IIIB-mC3d2-DNA (□), and sgp120IIIB-mC3d3-DNA (•). Assays used pooled serum samples from each mouse group that was normalized to the same OD (range, 1:200 to 1:400 for sgp120IIIB and sgp120IIIB-mC3d1; range, 1:800 to 1:3,200 for sgp120IIIB-mC3d2-DNA and sgp120IIIB-mC3d3). Data are the averages of three independent experiments.