Figure 3.
Film autoradiographs from a 35S-labeled probe revealed expression of L-PGDS mRNA in the parenchyma and, strongly, in the leptomeninges in control animals. (A) In the rostral POA, the area around the medial preoptic nucleus (MPO) and the VLPO showed the greatest level of expression. (B) Expression was still detected in the more caudal portions of the MPO and the lateral preoptic area (LPO). (C) In the hypothalamus, expression was most notable in the vl-VMN. (D) There was no specific hybridization signal when the control sense riboprobe was used.