Table 1. In vivo neutralization of anthrax toxin by MAP3 V/A.
Number of rats | PA/LF (μg) | First boost (μg) | Second boost (μg) | Outcome |
---|---|---|---|---|
Ten | 40/8 | – | – | All dead after 116 (±13) min |
Four | 40/8 | 250 | 250 | All dead after 140 (±1.4) min |
Four | 40/8 | 500 | – | All dead after 140.5 (±2) min |
Four | 40/8 | 500 | 500 | All alive |
Seven | 40/8 | 1000 | – | All alive |