Table 2. Genes whose expression varies with glycogen levels in the gastrocnemius.
Gastrocnemius microarray (fold-change) | ||||
---|---|---|---|---|
Gene symbol | Gene description | Unigene | MGSKO | GSL30 |
Metabolism | ||||
Gys1 | Glycogen synthase | Mm.275654 | −44.45* | 2.91 |
Hsd17β7 | Hydroxysteroid (17-β) dehydrogenase 7 | Mm.12882 | −2.35 | 1.73 |
Ugp2 | UDP-glucose pyrophosphorylase 2 | Mm.130747 | 1.59* | −1.59 |
Car14 | Carbonic anhydrase 14 | Mm.224836 | 1.88 | −1.85 |
Muscle/contractile proteins | ||||
Mylk | Myosin, light polypeptide kinase | Mm.247544 | 1.52 | −1.79* |
Utrn | Utrophin | Mm.331784 | 1.56 | −1.67 |
Atp1β1 | ATPase, Na+/K+ transporting, β1 polypeptide | Mm.4550 | 1.57 | −1.61† |
Atp2α2 | ATPase, Ca+2 transporting, cardiac muscle, slow-twitch 2 | Mm.227583 | 1.66 | −1.61‡ |
Myl2 | Myosin, light polypeptide 2, regulatory, cardiac, slow-twitch | Mm.1529 | 1.75 | −1.91 |
Tpm3 | Tropomyosin 3 | Mm.240839 | 1.84 | −2.39† |
Myh11 | Myosin, heavy polypeptide 11, smooth muscle | Mm.250705 | 1.98 | −2.19 |
Tncc | Troponin C, cardiac/slow-twitch skeletal | Mm.712 | 2.03 | −1.96 |
Tnnt1 | Troponin T1, skeletal, slow-twitch | Mm.711 | 2.13 | −2.44 |
Myl3 | Myosin, light polypeptide 3 | Mm.7353 | 2.10† | −1.73† |
Myh6 | Myosin, heavy polypeptide 6, cardiac muscle, α | Mm.290003 | 2.30* | −2.75a |
Receptors and signalling | ||||
Ppp1r1a | Protein phosphatase 1, regulatory (inhibitor) subunit 1A | Mm.143788 | −3.54 | 1.67 |
Tnfrsf19 | Tumour necrosis factor receptor superfamily, member 19 | Mm.281356 | −2.00* | 1.95* |
Map3k7 | Mitogen activated protein kinase kinase kinase 7 | Mm.258589 | −1.55 | 1.72* |
Adrβ2 | Adrenergic receptor, β2 | Mm.5598 | 1.52 | −1.78 |
C1qr1 | Complement component 1, q subcomponent, receptor 1 | Mm.681 | 1.54 | −1.58 |
Snrk | SNF related kinase | Mm.257989 | 1.56 | −1.54 |
Notch4 | Notch gene homologue 4 (Drosophila) | Mm.173813 | 1.56 | −1.75 |
Trpm7 | Transient receptor potential cation channel | Mm.244705 | 1.61 | −2.01 |
Bmp6 | Bone morphogenetic protein 6 | Mm.254978 | 1.62 | −1.79 |
Cxcl14 | Chemokine (C-X-C motif) ligand 14 | Mm.30211 | 1.63 | −1.57 |
Tie1 | Tyrosine kinase receptor 1 | Mm.4345 | 1.64 | −1.99 |
Adam15 | Disintegrin and metalloproteinase domain 15, metargidin | Mm.274049 | 1.68 | −1.57 |
Kitl | Kit ligand | Mm.45124 | 1.77 | −1.58 |
VEC/Cdh5 | VE-cadherin/cadherin 5, calcium ion-binding | Mm.21767 | 2.31 | −1.71 |
Nervous system | ||||
Mal | Myelin and lymphocyte protein, T-cell differentiation | Mm.39040 | 1.77 | −1.79 |
Mpz | Myelin protein zero | Mm.9986 | 3.51 | −1.71 |
Nucleic acid associated proteins | ||||
Dnase1 | Deoxyribonuclease I | Mm.239992 | −5.61 | 7.64 |
1700037B15Rik | RIKEN cDNA 1700037B15 gene | Mm.250841 | −2.52* | 1.68 |
Gadd45α | Growth arrest and DNA-damage-inducible 45 α | Mm.1236 | −1.74 | 1.75 |
5830411E10Rik | RIKEN cDNA 5830411E10 gene | Mm.196290 | −1.61 | 1.84 |
Eif4el3 | Eukaryotic translation initiation factor 4E like 3 | Mm.227183 | 1.57 | −2.08 |
AI255170 | Expressed sequence AI255170 | Mm.214973 | 2.01 | −2.41 |
Other | ||||
Tekt1 | Tektin 1 | Mm.42257 | −2.02 | 2.73 |
Sepr | Selenoprotein R | Mm.28212 | −1.53 | 1.58 |
Timp4 | Tissue inhibitor of metalloproteinases 4 | Mm.255607 | 1.55 | −1.58 |
Esam1 | Endothelial cell-specific adhesion molecule | Mm.41751 | 1.56 | −1.56 |
0610013D04Rik | RIKEN cDNA 0610013D04 gene | Mm.196330 | 1.76 | −1.64 |
1500005K14Rik | RIKEN cDNA 1500005K14 gene | Mm.34131 | 1.81 | −1.52 |
* Average of 2 probe sets detected in this experiment.
† Average of 3 probe sets detected in this experiment.
‡ Average of 4 probe sets detected in this experiment.