Table 3.

List of selected genes that are upregulated by BMP-2 in normal PASMC but downregulated in IPAH PASMC

Apoptotic inducers or proapoptotic factors	X59892: IFN-inducible γ2 protein
X83492: Fas/Apo-1	L77864: Stat-like protein (Fe65)
AF006041: Fas-binding protein (DAXX)	AL049176: Chordin-like protein/vWF type C domain
AF031167: Interleukin 15 precursor (IL-15)	AF022385: Apoptosis-related protein TFAR15
X82540: Activin β-C chain	U88666: Serine kinase SRPK2
M34064: N-cadherin	U89896: Casein kinase I γ2
D21255: OB-cadherin-2	U17714: Tumor suppressor ST13 (ST13)
M33308: Vinculin	AF061836: Tumor suppressor protein (RDA32)
M63838: Interferon-γ induced protein (IFI 16)
	Transcription factors
Membrane receptors, ion channels, transporters	X15218: Ski
U20860: Angiotensin II type 2 receptor gene	U47677: Transcription factor E2F1
D13168: Endothelin-B receptor (hET-BR)	X96717: Transcription factor TFE3
U01062: Inositol 1,4,5-trisphosphate receptor-3	J04111: c-Jun protooncogene
M58286: Tumor necrosis factor receptor	Z30093: Basic transcription factor 2t
U22662: Nuclear orphan receptor LXR-α	AF041259: Breast cancer transcription factor ZABC1
L00352: Low density lipoprotein receptor
AB026833: Chloride channel protein	Enzymes
U46569: Aquaporin-5 (AQP5) gene	D13146: 2 ,3 -cyclic-nucleotide 3 -phosphodiesterase
AJ010953: Ca2+-transporting ATPase	AL035079: Catalase
M95549: Na+/glucose cotransporter-like protein	U34683: Glutathione synthetase
AB016243: Regulatory factor 2 of Na+/H+ exchanger	Z82244: Heme Oxygenase 1 (HO-1)
U45285: Vacuolar H+ pump subunit (OC-116kDa)	M19961: Cytochrome c oxidase subunit Vb (coxVb)
	U46116: Receptor tyrosine phosphatase γ (PTPRG)
Signal transduction proteins and protein kinases	M64929: Protein phosphatase 2Aα subunit
U05770: Annexin V (ANX5)	X05409: Mitochondrial aldehyde dehydrogenase I
J04444: Cytochrome c-1	Y00264: Amyloid A4 precursor of Alzheimers disease
M68891: GATA-binding protein (GATA2)	M83772: Flavin-containing monooxygenase form II