Table 3.
# 1–6 from Table 1 | Penalty |
1 Yield: 87% | 6 |
2 H2O2 (30%, 4.1 mL, 36 mmol) | 0 |
Na2WO4·2H2O (66 mg, 0.2 mmol) | 0 |
[(Octyl)3NMe]HSO4 (93 mg, 0.2 mmol) | 0 |
Molecular sieves 4Å (100 mg) | 0 |
3 Benzyl chloride (T) | 5 |
4 Dropwise addition of H2O2 | 1 |
5 90°C, 10 h | 3 |
6 Extraction with AcOEt (3 × 10 mL) | 3 |
Washing with aq. Na2S2O4 | 3 |
Drying over MgSO4 | 0 |
Removal of AcOEt | 0 |
Crystallization from hexanes | 1 |
Penalty points total: | 22 |