FIG. 4.

vMA-1c kills ED cells that are chronically infected with wild-type EIAV but not chronically infected Cf₂Th cells. MA-1, vMA-1c, or pSP19-2 was incubated with (A) uninfected ED cells, (B) uninfected Cf₂Th cells, (C) chronically pSP19-2-infected ED cells, (D) chronically pSP19-2-infected Cf₂Th cells, (E) chronically MA-1-infected ED cells, or (F) chronically MA-1-infected Cf₂Th cells. All chronically infected cultures were >98% EIAV antigen positive at the time of superinfection. At the termination of the infections, cells were lysed and cellular ATP levels were determined with ATPLite-M as a measure of cell viability. Experiments were performed at least three times, and all treatments were performed in triplicate in each experiment. Shown are means of a representative experiment ± standard deviation of the mean. The percentage of the uninfected-control value is shown above each bar.