Table 2.
Top 33 dual regulated genes
| GenBank ID | AR | PR | Description | ||
| MPA | DHT | MPA | P | ||
| NM_005627 | 67.53 | 51.80 | 23.33 | 29.48 | Serum/glucocorticoid regulated kinase |
| AI985987 | 31.45 | 33.87 | 6.39 | 11.72 | Sodium channel, nonvoltage-gated 1, gamma |
| AI492388 | 26.17 | 11.44 | 37.57 | 31.08 | ti27d10.x1 NCI_CGAP_Kid11 Homo sapiens cDNA clone IMAGE:2131699 3', mRNA sequence. |
| AV707102 | 11.91 | 11.13 | 4.23 | 4.04 | Pyruvate dehydrogenase kinase, isoenzyme 4 |
| NM_004117 | 11.10 | 9.08 | 3.15 | 3.21 | FK506 binding protein 5 |
| AL556438 | 10.88 | 11.23 | 4.77 | 3.14 | TCDD-inducible poly(ADP-ribose) polymerase |
| AA404269 | 8.33 | 7.36 | 6.22 | 5.29 | Prickle-like 1 (Drosophila) |
| AB018580 | 7.54 | 5.38 | 4.74 | 4.69 | Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) |
| NM_005461 | 6.82 | 11.65 | 15.98 | 15.80 | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) |
| NM_001993 | 6.76 | 6.39 | 20.32 | 12.77 | Coagulation factor III (thromboplastin, tissue factor) |
| NM_001992 | 6.01 | 5.99 | 4.61 | 2.84 | Coagulation factor II (thrombin) receptor |
| BE219979 | 5.82 | 8.07 | 12.62 | 12.49 | Interleukin 20 receptor, alpha |
| NM_019018 | 5.06 | 4.63 | 8.18 | 8.43 | Hypothetical protein FLJ11127 |
| NM_006096 | 4.63 | 4.34 | 10.19 | 10.50 | N-myc downstream regulated gene 1 |
| NM_012429 | 4.42 | 4.95 | 4.06 | 3.76 | SEC14-like 2 (S. cerevisiae) |
| W86302 | 4.22 | 3.96 | 2.58 | 2.68 | FK506 binding protein 5 |
| AF288571 | 4.07 | 3.95 | 2.91 | 3.38 | Lymphoid enhancer-binding factor 1 |
| AW135013 | 4.00 | 8.54 | 16.37 | 13.28 | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) |
| BF593382 | 3.71 | 3.53 | 2.16 | 2.27 | Protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| AF131840 | 3.61 | 4.13 | 3.87 | 3.14 | SPRY domain-containing SOCS box protein SSB-1 |
| AA721025 | 3.47 | 3.00 | 5.59 | 3.30 | Homo sapiens transcribed sequence with moderate similarity to protein ref:NP_060265.1 (H.sapiens) |
| AI753747 | 3.32 | 3.23 | 2.46 | 2.22 | FK506 binding protein 5 |
| N73742 | 3.31 | 3.18 | 3.73 | 3.45 | Homo sapiens cDNA FLJ42287 fis, clone TLIVE2005866 |
| AA037766 | 3.27 | 2.81 | 3.17 | 2.56 | Homo sapiens LOC374963 (LOC374963), mRNA |
| AL357503 | 3.17 | 4.55 | 8.33 | 8.02 | Match: proteins: Tr:Q9UJ12 Tr:O43723 Tr:Q9VZN3 |
| NM_004235 | 3.06 | 4.89 | 4.69 | 4.83 | Kruppel-like factor 4 (gut) |
| BI668074 | 3.06 | 4.81 | 2.52 | 2.36 | 603295907F1 NIH_MGC_96 Homo sapiens cDNA |
| AL562398 | 2.82 | 2.24 | 2.12 | 2.14 | AL562398 Homo sapiens NEUROBLASTOMA COT 25-NORMALIZED |
| BG150485 | 2.78 | 2.88 | 2.79 | 2.03 | Solute carrier family 6 (neurotransmitter transporter, taurine), member 6 |
| BF056282 | 2.77 | 2.43 | 2.33 | 2.18 | Chromosome 9 open reading frame 52 |
| BF514079 | 2.73 | 4.33 | 8.09 | 7.66 | Kruppel-like factor 4 (gut) |
Shown are the top genes and their fold upregulation in Y-AR (AR+) and T47D (PR+) cells treated with physiologic concentrations of MPA and either DHT or progesterone. AR, androgen receptors; DHT, dihydrotestosterone; MPA, medroxyprogesterone acetate; P, progesterone; PR, progesterone receptor.