FIG. 3.

Neutralization of the homologous SF162 and heterologous SF2 viruses. The neutralizing potential of sera collected from the SF162gp140C-immunized (animals N472 [◊] and P655 [□]), ΔV2gp140C-immunized (animals H445 [▪] and J408 [▴]), and ΔV2gp140F-immunized (animals I708 [•] and K863 [⧫]) macaques against the SF162 and SF2 HIV-1 isolates was evaluated by determining the percent inhibition of PBMC infection at various dilutions. Results have been corrected for nonspecific inhibition of infection (i.e., in the presence of sera collected prior to the initiation of immunization). Results are the averages of three to six independent experiments.