TABLE 5.
Reduction in serum antibody gp120 binding in the presence of sCD4
| Animal no. | Immunogen | % Decrease in binding to gp120 proteina:
|
||
|---|---|---|---|---|
| SF162 | SF2 | US4 | ||
| J408 | ΔV2gp140C | 6 ± 2 | 7 ± 3 | 5 ± 3 |
| H445 | ΔV2gp140C | 15 ± 4 | 13 ± 7 | 5 ± 5 |
| I708 | ΔV2gp140F | 7 ± 2.5 | 14 ± 9 | 7 ± 3.5 |
| K863 | ΔV2gp140F | 19 ± 2 | 13 ± 4 | 5 ± 5 |
| N472 | SF162gp140C | 12.5 ± 8 | 5 ± 8 | 3 ± 5 |
| P655 | SF162gp140C | 5 ± 3 | 7 ± 10 | 1 ± 3 |
a
Values represent the percentages of decrease in serum antibody binding to the SF162, SF2, or US4 gp120 proteins in the presence of sCD4. Values are the averages ± standard deviations from two to six independent experiments.