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. 2003 Feb;23(4):1181–1195. doi: 10.1128/MCB.23.4.1181-1195.2003

FIG. 4.

FIG. 4.

Similar effects of ban and Trl loss-of-function mutations on the PRE-dependent pairing-sensitive silencing of white reporters. Three white deletion mutant alleles generated from banDf(2R)311a (39C and 35C) and banl(2)k02512 (Δ11Φ) were assayed in a heterozygous context for the pairing-sensitive silencing of either the X-linked, 3.8-kb Fab-7 PRE line 5F24 25,2 (5F24) (86), or the 260-bp iab-7 PRE line 260.1 (47). In the latter case, ban alleles were first recombined with the 260.1 insertion on the second chromosome. In all cases (35C/+ and Δ11Φ/+ in 5F24 25,2 females and 39C 260.1 males and females), derepression of the white transgene was observed in ban heterozygotes, closely resembling what is observed in Trl13c (Trl-/+) heterozygotes. Derepression was increased in double heterozygotes 39C 260.1/260.1; Trl13c/+ (39C/+; Trl-/+). For each combination, effects were compared between siblings of the same gender and the appropriate genotype.