Table 6.
Conserved UPR cis-Acting Elements in Arabidopsisd
| Abundancea
|
||||||
|---|---|---|---|---|---|---|
| Name of cis Element |
Sequence of cis Element |
Arabidopsis Genome (24,598) |
8K GeneChip (7,372) |
UPR Downregulated Genes (129) |
UPR Upregulated Genes (53) |
Genes |
| Motif I | CCACGTCA | 862 | 282 (249)b | 5 (4.93)c | 9 (2.03)c | BiP, CNX1, PDI (At2g47470), HSP-90,HSP-like, Ca-ATPase4, At2g44080, similar to vesicle trafficking, At4g01810 |
| Motif II | CC-N12-CCACG | 1010 | 265 (292) | 7 (4.64) | 15 (1.91) | SAR1B, HSP-90, SBP-like, At4g10040, GPT, Ca-ATPase4, CNX1, AtUtr1, PDI (At2g47470), At4g11800, At4g14430, Ca-kinase, HSP-like, At4g34630, GST, ATAF2 |
| Mammalian UPRE | TGACGTGAc (tcacgtca) | 488 | 126 (141) | 0 (2.2) | 0 (0.91) | |
| Yeast UPRE | CAGCGTG | 453 | 118 (131) | 0 (2.07) | 2 (0.85) | BIP-like, At4g02880 |
| Mammalian ERSE-I | CCAAT-N9-CCACG | 202 | 64 (58) | 2 (1.12) | 7 (0.46) | CNX1, HSP-90, HSP-like, SBP-like, Ca-ATPase4, GPT, ATAF2 |
| Mammalian ERSE-II | ATTGG-N-CCACG | 41 | 21 (11.93) | 0 (0.37) | 2 (0.15) | BiP, Ca-kinase |
a
Occurrence based on the number of predicted sequences in the Arabidopsis genome at the time of this analysis and on independent genes in the 8K Affymetrix GeneChip. Total number of genes is shown in parentheses.
b
Numbers in parentheses in this column are expected numbers based on total detected in the Arabidopsis genome.
c
Numbers in this column are corrected based on occurrence in the Affymetrix GeneChip.
d
Alternative mammalian UPRE. The reverse sequence is shown in parentheses.