Table 1.
Ontology term | rRNA | Prot | Ubiq | ||||||
DNA Dmg | Env Stress | Cell Cycle | DNA Dmg | Env Stress | Cell Cycle | DNA Dmg | Env Stress | Cell Cycle | |
35S primary transcript processing | 1E-17 | 8.8E-16 | 7.5E-16 | 0.17 | 0.51 | 0.52 | 0.26 | 1 | 0.16 |
processing of 20S pre-rRNA | 2E-32 | 5E-19 | 3.8E-32 | 0.018 | 0.37 | 1 | 0.17 | 1 | 0.11 |
ribosomal large subunit biogenesis | 9.6E-13 | 0.0000071 | 3.5E-15 | 0.38 | 1 | 0.38 | 1 | 1 | 0.62 |
rRNA modification | 2.1E-08 | 0.0043 | 0.00014 | 0.66 | 0.019 | 0.00066 | 1 | 1 | 0.62 |
rRNA processing | 1.2E-25 | 1.6E-16 | 2.5E-23 | 0.48 | 1 | 0.62 | 0.11 | 1 | 0.046 |
protein biosynthesis | 0.0001 | 1.1E-11 | 0.0023 | 5.9E-83 | 5.6E-108 | 1.4E-80 | 0.53 | 0.42 | 0.00033 |
translational elongation | 0.62 | 0.14 | 0.63 | 2.1E-08 | 3E-08 | 1.7E-09 | 1 | 1 | 0.64 |
translational initiation | 0.19 | 1 | 0.025 | 0.000017 | 1.8E-14 | 3.4E-07 | 0.41 | 1 | 0.25 |
ubiquitin-dependent protein catabolism | 0.039 | 0.02 | 0.071 | 0.027 | 0.048 | 0.018 | 2.5E-25 | 7.3E-25 | 6.3E-17 |
ATP-dependent RNA helicase activity | 7.2E-11 | 9.2E-08 | 4.1E-11 | 0.39 | 0.62 | 1 | 1 | 1 | 0.62 |
DNA-directed RNA polymerase activity | 6.1E-13 | 4E-08 | 1.4E-09 | 0.77 | 0.012 | 0.13 | 0.42 | 1 | 0.4 |
snoRNA binding | 1.3E-27 | 7.6E-17 | 2.4E-25 | 0.042 | 0.51 | 0.76 | 0.42 | 1 | 0.16 |
structural constituent of ribosome | 0.00012 | 2.2E-11 | 0.000078 | 3.1E-92 | 5.3E-117 | 1.8E-95 | 0.097 | 0.41 | 0.0021 |
translation initiation factor activity | 0.16 | 0.48 | 0.14 | 4.7E-08 | 5.5E-17 | 2.3E-10 | 1 | 1 | 0.39 |
endopeptidase activity | 0.25 | 0.21 | 0.62 | 0.16 | 0.62 | 0.39 | 9.2E-21 | 2.6E-18 | 2.7E-11 |
nucleolus | 1.6E-48 | 3.4E-29 | 1.3E-45 | 0.18 | 0.65 | 0.84 | 0.021 | 0.48 | 0.0056 |
nucleus | 1.2E-18 | 8.3E-13 | 7.8E-10 | 0.0053 | 2.1E-07 | 0.12 | 0.0048 | 1 | 0.033 |
small nucleolar ribonucleoprotein complex | 7.9E-20 | 2.8E-09 | 1.3E-14 | 0.16 | 0.67 | 0.42 | 0.63 | 1 | 0.39 |
cytosolic large ribosomal subunit | 0.03 | 0.0000016 | 0.0087 | 2.1E-65 | 3.4E-75 | 6.1E-67 | 0.021 | 1 | 0.0056 |
cytosolic small ribosomal subunit | 0.059 | 0.0013 | 0.26 | 1.5E-41 | 1.2E-47 | 4.6E-42 | 0.073 | 1 | 0.03 |
ribosome | 1 | 0.39 | 0.3 | 2.7E-09 | 6.2E-14 | 3.7E-09 | 1 | 1 | 0.62 |
*For each module in each dataset analyzed, an EASE analysis [25] was performed by using Fisher's exact test and the resulting p-values were placed into the table based on the prevalence of the GO (Gene Ontology) term being searched for. The most significant enrichments for a given term are indicated in italics