Table 1.
The effect of genetic and environmental variables upon lifespan in the presence of blueberry polyphenols
| Mean lifespan, SEM (n) | ||||
|---|---|---|---|---|
| Genotype | Treatment | Control | Treated | Change |
| fem-1(hc17) | BB crude | 12.1, 0.63 (73) | 16.6, 0.46 (46) | 1.37* |
| ‘’ | BB 25 °C | 12.7, 0.23 (362) | 16.2, 0.23 (350) | 1.28** |
| ‘’ | BB 20 °C | 16.1, 0.26 (237) | 18.7, 0.26 (210) | 1.16** |
| ‘’ | BB 15 °C | 22.9, 0.74 (44) | 22.2, 0.92 (38) | 0.97 |
| ‘’ | amp | 13.1, 0.66 (60) | 17.5, 0.56 (66) | 1.34** |
| ‘’ | amp + BB | 13.1, 0.66 (60) | 18.1, 0.46 (70) | 1.38** |
| mev-1(kn1) | BB | 9.1, 0.28 (101) | 8.6, 0.28 (98) | 0.95 |
| sir-2(ok434) | BB | 12.2, 0.54 (76) | 15.9, 0.58 (68) | 1.30** |
| osr-1(rm1) | BB | 16.3, 0.31 (151) | 15.7, 0.37 (78) | 0.96 |
| unc-43(n1186) | BB | 13.1, 0.31 (108) | 12.8, 0.48 (61) | 0.98 |
| sek-1(ag1) | BB | 11.7, 0.73 (33) | 10.9, 0.64 (26) | 0.93 |
| daf-16(mgDf50) | BB | 10.2, 0.38 (53) | 12.3, 0.34 (42) | 1.21** |
| ‘’ | amp | 11.5, 0.38 (53) | 12.7, 0.38 (53) | 1.10* |
| ‘’ | amp + BB | 11.5, 0.38 (53) | 14.7 0.38 (53) | 1.28** |
| skn-1(zu67) | BB | 9.9, 0.52 (36) | 13.1, 0.54 (43) | 1.32** |
*
P ≤ 0.05,
**
P ≤ 0.001, log-rank. Aging assays performed at 25 °C, unless noted, except mev-1(kn1) which was carried out at 25 °C and 20 °C, with or without FUDR, with similar results. Treatments: crude at 1.5 mg mL−1; BB, BB polyphenols at 200 µg mL−1; amp, ampicillin at 100 µg mL−1.