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PLD1 rescues the impaired budding of βAPP-containing vesicles in FAD-linked PS1 mutant cells. (a) Kinetics of βAPP-containing vesicle formation was analyzed in N2a PS1ΔE9 cells transiently transfected with PLD1 wt cDNA or PLD1 K898R cDNA and compared with mock transfections. (b) The amount of βAPP in budded vesicles was expressed as the percentage of total βAPP.
