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. 2006 Feb 7;103(7):2184–2189. doi: 10.1073/pnas.0510577103

Fig. 2.

Fig. 2.

All LT repopulating bone marrow HSC cells express surface PrP. A total of 1 × 105 PrP− or 2 × 104 PrP+ CD45.2 donor BM cells (A), 2 × 104 PrP+ CD45.2 donor BM cells (B), 500 sorted Lin−Sca-1+PrP− or 100 Lin−Sca-1+PrP+ CD45.2 donor BM cells (C), or 500 isolated SP PrP− or 250 SP PrP+ donor BM cells (D) were mixed with 1 × 105 competitor CD45.1 cells and transplanted into lethally irradiated CD45.1 mice (n = 4–5). (A) Donor CD45.2 contribution at 4 weeks and 6 months after transplant. (B) Multilineage contribution at 6 months after transplant. (C) Donor contribution at 3 weeks and 4 months after transplant. (D) Donor contribution at 4 months after transplant.