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. 2006 Feb 1;103(7):2208–2213. doi: 10.1073/pnas.0510839103

Fig. 5.

Fig. 5.

Gene expression in Shhcre;Dicer lungs. Shown is whole-mount RNA in situ analysis of Fgf10, Spry2, and Bmp4 expression in control and mutant lungs at E12.5 (A–F) and E11.75 (G–L). At E12.5, the expression of all three genes was increased in the mutant compared with control. At E11.75, Fgf10 expression was increased in the mutant, whereas Spry2 and Bmp4 expression was not changed compared with control. Note that in B and H, despite Fgf10 up-regulation, there were still regional differences in expression level within each of the mutant lungs, similar to controls in A and G.