Fig. 2.
Effects of CTZ on the AMPA dose/current–response relationship. Typical whole-cell currents induced in two different cells by AMPA alone (A) or by AMPA plus CTZ (different cell from A) (B). (C) AMPA dose/peak current response to AMPA alone (•) or in the presence of 50 μM CTZ (○). Imax = −524 ± 184 pA (control); I = −5.8 ± 1.1 nA with CTZ (n = 5). In the control, EC50 and nH values were 139 μM and 2.65, respectively. With CTZ at the indicated concentration, EC50 and nH values were 18 μM and 1.27, respectively.
