Table 3.
Conservation of MER121, relative to typical ancestral repeat elements
| MER121 | MER119 | L2 | Significance* | |
|---|---|---|---|---|
| Retention across HDMR† | 82% | 28% | 37% | P < 10−100 |
| Length ratio relative to human‡ | 1.00 (0.05) | 0.89 (0.22) | 0.91 (0.22) | P < 10−27 |
| Four-way aligned bases§ | 96% | 73% | 69% | P < 10−100 |
| Four-way sequence identity¶ | 72% | 49% | 48% | P < 10−100 |
*Significance levels based on binomial test for proportions; Wilcoxon test for the length ratio. Significance levels below 10−100 are capped at this value.
†Proportion of human copies with orthologous copies in each of dog, mouse, and rat.
‡Median length ratio for mouse repeat relative to human repeat, for orthologous copies. Interquartile range is shown in parentheses.
§Proportion of human bases aligning to (ungapped) bases in each of dog, mouse, and rat. The values for MER119 and L2 are similar to the average across all ARs.
¶Proportion of four-way aligned bases that are identical across all four species. The values for MER119 and L2 are similar to the average across all ARs.