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Structure and self-assembly of fragments 1 and 2. (A) Amino acid sequence of fragments 1 and 2. The glycine residue preceding the adjacent cysteines in the α2 strand establishes the requisite register for triple-helix formation with the identical α1 and α1′ strands. Hyp, (2S,4R)-4-hydroxyproline. (B) Representation of the self-assembly process; green, red, and blue are used simply to distinguish individual fragments.
