Table 1.

Patient characteristics and hemostatic variables before antithrombin substitution

Patient no.	Diagnosis	Organism	Age (years)	APACHE II score	PT (%)	aPTT (sec)	Fibrinogen (mg/dl)	AT (%)	D-dimer (μg/l)	Thrombocyte count	Outcome
1	Pneumonia, SBP	Staphylococcus aureus	56	38	30	73	263	20	2,374	47,000	Died
2	Pneumonia, SBP	Staphylococcus aureus	31	43	18	58	198	23	2,177	24,000	Died
3	SBP	No organism	56	39	37	51	266	39	976	38,000	Survived
4	Pneumonia	Fusobacterium necrophorum	19	35	71	56	490	36	999	55,000	Survived
5	Pneumonia	Streptococcus pneumoniae	50	28	37	77	290	34	6,500	89,000	Survived
6	Pneumonia, AML	Klebsiella sp.	61	30	45	45	80	53	6,500	87,000	Died
7a	Pneumonia, AML	Escherichia coli	62	32	60	50	690	34	1,368	11,000	Survived
8a	Pneumonia	Staphylococcus epidermidis	21	27	52	54	602	36	1,291	31,000	Survived

^aPatients who received concomitant low-dose heparin. AT, antithrombin; aPTT, activated partial thromboplastin time; PT, prothrombin time. SBP = spontaneous bacterial peritonitis, AML = acute myelogenous leukemia