FIGURE 5.

Comparison of mechanical models with cell deformation data. (A) An HL60 cell was indented at 24 nm/s. The Hertzian mechanics model (dashed line) fits the data (gray line) better than the liquid droplet model (dotted line). Contact point is denoted by the circle. (B) A sphere shaped indenter with a diameter of 10 μm was attached to the end of the cantilever and pushed into a different cell at 415 nm/s. The Hertzian mechanics (dashed line) and liquid droplet (dotted line) models were modified for a spherical punch and were fit to the data (gray line). Again, the Hertz model was a better fit to the data.