. 2005 Feb;4(1):37–44.

Table 3.

Average cost-effectiveness of interventions at specified levels of coverage (I$ per DALY averted)

		World Bank Region
		Sub-Saharan	Latin America	Middle East	Europe	South	East Asia
		Africa	& Caribbean	& North Africa	& Central Asia	Asia	& Pacific
Total population (million)		640	502	482	462	1,242	1,827
	Coverage
Schizophrenia¹
Older (neuroleptic) antipsychotic drug	80%	5,202	13,369	6,882	12,260	4,482	8,760
Newer antipsychotic drug	80%	18,497	26,199	19,594	25,693	17,991	22,010
Older antipsychotic drug +	80%	3,314	8,993	4,511	10,089	2,887	5,814
psychosocial treatment	80%	3,314	8,993	4,511	10,089	2,887	5,814
Newer antipsychotic drug +	80%	11,669	17,352	12,562	20,627	11,354	14,281
psychosocial treatment	80%	11,669	17,352	12,562	20,627	11,354	14,281

Bipolar disorder¹
Older mood stabilising drug (lithium)	50%	3,025	8,706	6,122	8,051	3,302	6,103
Newer mood stabilising drug (valproate)	50%	4,829	10,074	6,935	9,620	4,422	7,230
Older mood stabilising drug +	50%	2,903	7,785	5,492	7,233	3,136	5,524
psychosocial treatment	50%	2,903	7,785	5,492	7,233	3,136	5,524
Newer mood stabilising drug +	50%	4,520	8,988	6,222	8,607	4,147	6,530
psychosocial treatment	50%	4,520	8,988	6,222	8,607	4,147	6,530

Depression
Episodic treatment: older	50%	1,026	2,219	1,193	2,178	924	1,469
antidepressant drug (TCA)	50%	1,026	2,219	1,193	2,178	924	1,469
Episodic treatment: newer	50%	1,396	2,518	1,531	2,526	1,290	1,801
antidepressant drug (SSRI)	50%	1,396	2,518	1,531	2,526	1,290	1,801
Episodic psychosocial treatment	50%	1,384	2,726	1,499	2,494	1,205	1,787
Episodic psychosocial treatment +	50%	1,416	2,595	1,487	2,421	1,256	1,738
older antidepressant	50%	1,416	2,595	1,487	2,421	1,256	1,738
Episodic psychosocial treatment +	50%	1,819	2,982	1,866	2,860	1,641	2,125
newer antidepressant	50%	1,819	2,982	1,866	2,860	1,641	2,125
Maintenance psychosocial treatment +	50%	1,706	2,935	1,721	2,589	1,547	1,968
older antidepressant	50%	1,706	2,935	1,721	2,589	1,547	1,968
Maintenance psychosocial treatment +	50%	2,245	3,460	2,229	3,162	2,072	2,487
newer antidepressant	50%	2,245	3,460	2,229	3,162	2,072	2,487

Panic disorder
Anxiolytic drug (benzodiazepine)	50%	1,277	1,853	1,237	1,748	997	1,332
Older antidepressant	50%	1,013	1,378	984	1,328	842	1,057
drug (TCA)	50%	1,013	1,378	984	1,328	842	1,057
Newer antidepressant drug	50%	1,174	1,519	1,135	1,481	1,010	1,219
(SSRI; generic)	50%	1,174	1,519	1,135	1,481	1,010	1,219
Psychosocial treatment (CBT)	50%	1,276	1,666	1,145	1,702	970	1,271
Older antidepressant +	50%	1,583	1,942	1,440	1,983	1,303	1,584
psychosocial treatment	50%	1,583	1,942	1,440	1,983	1,303	1,584
Newer antidepressant +	50%	1,722	2,061	1,570	2,121	1,441	1,720
psychosocial treatment	50%	1,722	2,061	1,570	2,121	1,441	1,720

Results for community-based service model presented here only (hospital-based service model not shown); CBT - cognitive behavioural therapy; DALYs - disability- adjusted life years; SSRI - selective serotonin reuptake inhibitor; TCA - tricyclic antidepressant