Table 2.

The dia2 mutant interacts genetically with checkpoint mutants

dia2 Double mutants	Role	Phenotype
DNA damage
rad9	Adaptor	Slower growth at 16 and 25°C
rad17	Clamp loader	Slower growth at 30°C
rad24	Clamp loader	Slower growth at 30°C
Kinases
mec1 sml1	Transducer kinase	Inviable
chk1	Transducer kinase	Slower growth at 25°C
DNA replication
mrc1	Adaptor	Slower growth at 25°C, inviable at 37°C
Targets
pds1	Cohesin	Inviable
cdc20-1	APC activator	Inviable