Figure 6.

Effects of dynein, kinesn-1, and dynactin mutations on anterograde and retrograde class duty cycles. The percentage of time spent in anterograde runs, pauses, and retrograde runs for anterograde and retrograde class mitochondria are shown for the following genotypes: +/+, wild-type (for both A and B, n = 52 mitochondria in 5 larvae); D/D, Dhc64C^6-10/Dhc64C^4-19 (for A, n = 92 and 5; for B, n = 11 and 5); D/+, Dhc64C^4-19/+ (for A, n = 44 and 5; for B, n = 43 and 5); K⁶/K, Khc⁶/Khc²⁷ (for A, n = 24 and 4; for B, n = 5 and 4); K/+, Khc27/+ (for A, n = 85 and 5; for B, n = 118 and 5); and G/+) Gl¹/+ (for A, n = 94 and 5; for B, n = 64 and 5). Bars show SEs. Values can be found in Table 1 and Supplemental Table s1. Means showing a genotype by genotype contrast significance of p ≤ 0.05 compared with wild type are noted by an asterisk.