Table 1.
Frequencies of PARP1 signals at telomeres in untreated or radiation-treated HeLa1.2.11 cells
| Cell type | No. of chromosome-associated PARP1/no. of chromosomesa | No. of telomere-associated PARP1/no. of chromosomesb | No. of SFE-associated PARP1/no. of SFEsc |
|---|---|---|---|
| Untreated | 22/1523 (0.014) | 3/1523 (0.002) | 0/4 (0) |
| X-ray (5 Gy) | 1552/1666 (0.932)d | 329/1666 (0.197)d | 58/196 (30) |
a
Average number of PARP1 signals per chromosome. PARP1 signals include both chromosomal interiors and telomeres.
b
Average number of telomere-associated PARP1 signals per chromosome.
c
% SFEs positive for PARP1 signals in parentheses. Each chromosome is counted for four ends (for example, 1523 chromosomes of untreated cells have 6092 ends. Among those ends, four ends have SFEs).
d
p value between treated and untreated yielded a statistical difference of p < 0.01, using a chi-square test.