TABLE 2.
List of GO biological processes associated with significantly upregulated genes
| Affymetrix identifier | Gene description | Gene symbol | Change (n-fold) |
|---|---|---|---|
| Cytokine biosynthesis (z score = 9.9) | |||
| 1450297_at | Interleukin 6 | Il6 | 6.77 |
| 1418901_at | CCAAT/enhancer binding protein (C/EBP); beta | Cebpb | 2.10 |
| 1427705_a_at | Nuclear factor of kappa light chain gene enhancer in B cells 1; p105 | Nfkb1 | 2.10 |
| 1419536_a_at | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Rela | 1.97 |
| 1449399_a_at | Interleukin 1 beta | Il1b | 1.77 |
| 1448436_a_at | Interferon regulatory factor 1 | Irf1 | 1.75 |
| Acute-phase response (z score = 7.7) | |||
| 1449326_x_at | Serum amyloid A2 | Saa2 | 38.88 |
| 1450788_at | Serum amyloid A1 | Saa1 | 35.86 |
| 1450826_a_at | Serum amyloid A3 | Saa3 | 22.64 |
| 1450297_at | Interleukin 6 | Il6 | 6.77 |
| 1426587_a_at | Signal transducer and activator of transcription 3 | Stat3 | 2.30 |
| 1448881_at | Haptoglobin | Hp | 2.25 |
| Inflammatory response (z score = 9.1) | |||
| 1449984_at | Chemokine (C-X-C motif) ligand 2 | Cxcl2 | 103.92 |
| 1419209_at | Chemokine (C-X-C motif) ligand 1 | Cxcl1 | 37.37 |
| 1418930_at | Chemokine (C-X-C motif) ligand 10 | Cxcl10 | 23.16 |
| 1417483_at | Molecule possessing arikyrin repeats induced by lipopolysaccharide | IkappaB-zeta | 13.86 |
| 1417268_at | CD14 antigen | Cd14 | 10.07 |
| 1419132_at | Toll-like receptor 2 | Tlr2 | 5.14 |
| 1419561_at | Chemokine (C-C motif) ligand 3 | Ccl3 | 3.56 |
| 1420558_at | Selectin; platelet | Selp | 3.54 |
| 1420380_at | Chemokine (C-C motif) ligand 2 | Ccl2 | 3.38 |
| 1423954_at | Complement component 3 | C3 | 2.37 |
| 1422029_at | Chemokine (C-C motif) ligand 20 | Ccl20 | 2.21 |
| 1421228_at | Chemokine (C-C motif) ligand 7 | Ccl7 | 2.08 |
| 1457676_at | Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein | Tirap | 1.97 |
| 1418162_at | Toll-like receptor 4 | Tlr4 | 1.96 |
| 1449874_at | Lymphocyte antigen 96 | Ly96 | 1.93 |
| 1449399_a_at | Interleukin 1 beta | Il1b | 1.77 |
| Chemotaxis (z score = 2.1) | |||
| 1449984_at | Chemokine (C-X-C motif) ligand 2 | Cxcl2 | 103.92 |
| 1419394_s_at | S100 calcium binding protein A8 (calgranulin A) | S100a8 | 79.99 |
| 1418930_at | Chemokine (C-X-C motif) ligand 10 | Cxcl10 | 23.16 |
| 1419561_at | Chemokine (C-C motif) ligand 3 | Ccl3 | 3.56 |
| 1420380_at | Chemokine (C-C motif) ligand 2 | Ccl2 | 3.38 |
| 1449195_s_at | Chemokine (C-X-C motif) ligand 16 | Cxcl16 | 2.36 |
| 1422029_at | Chemokine (C-C motif) ligand 20 | Ccl20 | 2.21 |
| 1421228_at | Chemokine (C-C motif) ligand 7 | Ccl7 | 2.08 |
| 1449399_a_at | Interleukin 1 beta | Il1b | 1.77 |
| Cell proliferation (z score = 2.7) | |||
| 1419209_at | Chemokine (C-X-C motif) ligand 1 | Cxcl1 | 37.37 |
| 1449731_s_at | Nuclear factor of k light chain gene enhancer in B cells inhibitor alpha | Nfkbia | 5.76 |
| 1448830_at | Dual-specificity phosphatase 1 | Dusp1 | 5.73 |
| 1415899_at | Jun-B oncogene | Junb | 5.49 |
| 1419208_at | Mitogen-activated protein kinase kinase kinase 8 | Map3k8 | 4.66 |
| 1423100_at | FBJ osteosarcoma oncogene | Fos | 4.33 |
| 1449773_s_at | Growth arrest and DNA-damage-inducible 45 beta | Gadd45b | 4.05 |
| 1426083_a_at | B-cell translocation gene 1; anti-proliferative | Btg1 | 3.67 |
| 1417314_at | Histocompatibility 2; complement component factor B | H2-Bf | 3.56 |
| 1425379_at | Hepatocyte growth factor | Hgf | 3.42 |
| 1417409_at | Jun oncogene | Jun | 3.16 |
| 1451318_a_at | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | Lyn | 2.92 |
| 1420623_x_at | Heat shock protein 8 | Hspa8 | 2.66 |
| 1417558_at | Fyn proto-oncogene | Fyn | 2.60 |
| 1416268_at | E26 avian leukemia oncogene 2; 3′ domain | Ets2 | 2.36 |
| 1417856_at | Avian reticuloendotheliosis viral (v-rel) oncogene-related B | Relb | 2.15 |
| 1419536_a_at | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | Rela | 1.97 |
| 1417450_a_at | Transforming, acidic coiled-coil-containing protein 3 | Tacc3 | 1.88 |
| 1423401_at | ets variant gene 6 (TEL oncogene) | Etv6 | 1.86 |
| 1418936_at | v-maf musculoaponeurotic fibrosarcoma oncogene family; protein F | Maff | 1.82 |
| 1434005_at | Single-stranded interacting protein 1 | Rbms1 | 1.79 |
| 1449399_a_at | Interleukin 1 beta | Il1b | 1.77 |
| 1425393_a_at | Mitogen-activated protein kinase kinase 7 | Map2k7 | 1.74 |
| 1422414_a_at | Calmodulin 2 | Calm2 | 1.73 |
| Apoptosis (z score = 2.1) | |||
| 1450297_at | Interleukin 6 | Il6 | 6.77 |
| 1449591_at | Caspase 11; apoptosis-related cysteine protease | Casp11 | 5.54 |
| 1421392_a_at | Baculoviral IAP repeat containing 2 | Birc3 | 5.16 |
| 1449773_s_at | Growth arrest and DNA damage-inducible 45 beta | Gadd45b | 4.05 |
| 1419004_s_at | B-cell leukemia/lymphoma 2-related protein A1a | Bcl2a1a | 3.04 |
| 1450829_at | Tumor necrosis factor alpha-induced protein 3 | Tnfaip3 | 2.65 |
| 1416881_at | Myeloid cell leukemia sequence 1 | Mcl1 | 2.30 |
| 1418901_at | CCAAT/enhancer binding protein (C/EBP) beta | Cebpb | 2.10 |
| 1427705_a_at | Nuclear factor of kappa light chain gene enhancer in B cells 1; p105 | Nfkb1 | 2.10 |
| 1418854_at | Baculoviral IAP repeat-containing 3 | Birc2 | 1.92 |
| 1417045_at | BH3-interacting domain death agonist | Bid | 1.83 |