FIG. 2.

MyD88 deficiency results in the B. burgdorferi infection-induced development of myositis, glomerulonephritis, alveolitis, and pancreatitis. MyD88^−/− and MyD88^+/+ mice were infected with B. burgdorferi as described in Materials and Methods and were sacrificed 3 weeks after infection. Representative HE-stained sections of muscle (A and B), kidney (C and D), lungs (E and F), and pancreas (G and H) of both MyD88^−/− mice (A, C, E, and G) and wild-type littermate MyD88 control mice (B, D, F, and H) are shown. The insets are the magnified views of the areas in the boxes.