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Pathology of IL-18-deficient mice infected with B. burgdorferia
| Genotype | Avg score ± SD (no. of mice)
|
|
|---|---|---|
| Joint | Heart | |
| IL-18+/+ | 1.6 ± 0.55 (5) | 1.7 ± 0.488 (7) |
| IL-18−/− | 1.6 ± 0.5 (10) | 1.4 ± 0.224 (5) |
| P | 0.81 | 0.115 |
The overall histopathology was scored in a blinded manner on a scale of 0 (no lesion) to 5 (severe lesion), and the average of all scores for each group is shown.
