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. 2006 Mar;74(3):1452–1461. doi: 10.1128/IAI.74.3.1452-1461.2006

TABLE 1.

Identification of genes that are enhanced by H. pylori infectiona

Gene type and accession no. Gene name Fold change
Apoptosis-related genes
    NM_001165 cIAP2(BIRC3) 5.3
    NM_014350 GG2-1 3.7
    NM_003806 HRK(harakiri) 2.9
    NM_021960 MCL1 2.1
Signal transduction-related genes
    NM_020529 IκBα (NFKBIA) 2.7
    NM_021913 AXL 2.2
    NM_002401 MAP3K3 1.7
    NM_005043 MAP2K7 1.7
Immune response-related genes
    NM_000584 IL-8 7.8
    NM_001511 CXCL1 6.3
    NM_002089 CXCL2 2.3
    NM_002090 CXCL3 3.5
    NM_003811 TNFSF9 1.7
Regulation of transcription
    NM_002729 HHEX 3.1
    NM_003998 NF-κB 1 (p105) 2.6
    NM_006509 RelB 2.4
    NM_138714 NFAT5 2.4
    NM_001300 COPEB 2.2
    NM_001730 KLF5 1.8
    NM_002228 JUN 1.8
    NM_005902 MADH3 1.7
    NM_006147 IRF6 1.5
Cell surface receptor
    NM_000640 IL13RA2 5.1
    NM_005534 IFNGR2 1.9
    NM_000201 ICAM1 1.8
    NM_012211 ITGA11 1.6
G-protein-coupled receptor protein
    NM_002082 GPRK6 4.3
    X64980 HTPCRX02 3.4
    NM_005274 GNG5 1.9
    NM_005308 GPRK5 1.8
Proteolysis and peptidolysis
    NM_002421 MMP1 3.7
    NM_002543 OLR1 1.8
    NM_002425 MMP10 1.8
Cytoskeleton-related genes
    NM_012334 MYO10 2.7
    X13100 Myosin heavy chain 2.7
    NM_000526 KRT14 1.6
    NM_005557 KRT16 1.6
Others
    NM_000041 APOE 14.6
    NM_030952 SNARK 9.6
    NM_014172 PHP14 4.3
    NM_000499 CYP1A1 3.2
    NM_002526 NT5E 3.2
    NM_004583 RAB5C 2.4
    NM_000527 LDLR 2.4
    NM_001731 BTG1 2.4
    NM_002999 SDC4 2.2
    NM_001142 AMELX 2.1
a

Microarray analysis was performed in duplicate, as described in Materials and Methods. The genes shown in this table are representative genes that were up-regulated more than 1.5-fold in both arrays. For each functional category of genes, the GenBank accession number, the common name, and the mean signal ratio are indicated.