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FIG. 4.

FIG. 4.

Serum antibody to B. pseudomallei K96243 in immunized animals. Animals were immunized with either DCs that were pulsed with heat-killed B. pseudomallei K96243, DCs that were pulsed with heat-killed bacteria in the presence of CpG 1826 (6 mg ml−1), or DCs that were pulsed with heat-killed bacteria with CpG 1826 coadministered as an adjuvant (75 mg). Each bar represents the mean of the antibody titers with the standard error of the mean in samples from 10 individuals. The CpG-treated groups produced significantly more antibody (P < 0.01) than did the group treated with DC only.