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Gross pathology of infected and treated lungs. Shown are lungs from piglets infected with 5 × 109 CFU of B. pertussis and treated with 500 μg pBD-1 at (A) 2 days and (B) 4 days postchallenge or untreated infected control (saline-treated) piglets at (C) 2 and (D) 4 days after challenge. Results shown are representative of three experiments, with at least three piglets per time point.
