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. 2006 Apr;74(4):2031–2042. doi: 10.1128/IAI.74.4.2031-2042.2006

TABLE 1.

Liver parasitism in the acute phase of T. cruzi infectiona

No. of days p.i. No. of amastigote nests/liver slide in mouse strain:
WT IFN-γ KO CD4 KO CD8 KO
9 ND 1.4 ± 1.2 ND ND
13 0.2 ± 0.3 >50.0 9.8 ± 3.8 12.3 ± 3.0
16 ND 0.3 ± 0.5 1.2 ± 2.1
20 ND 0.3 ± 0.5 1.2 ± 1.3
a

Wild-type and deficient mice infected by Y strain T. cruzi parasites were sacrificed at the indicated days, and their livers were analyzed for the presence of amastigote nests. Results represent the mean (±SD) amastigote nests of six non-consecutive hematoxilin-eosin stained slides, for each mouse, for five mice from each group and time point. Results from a representative experiment out of two experiments are shown. ND, not detected.