TABLE 1.
No. of days p.i. | No. of amastigote nests/liver slide in mouse strain:
|
|||
---|---|---|---|---|
WT | IFN-γ KO | CD4 KO | CD8 KO | |
9 | ND | 1.4 ± 1.2 | ND | ND |
13 | 0.2 ± 0.3 | >50.0 | 9.8 ± 3.8 | 12.3 ± 3.0 |
16 | ND | 0.3 ± 0.5 | 1.2 ± 2.1 | |
20 | ND | 0.3 ± 0.5 | 1.2 ± 1.3 |
Wild-type and deficient mice infected by Y strain T. cruzi parasites were sacrificed at the indicated days, and their livers were analyzed for the presence of amastigote nests. Results represent the mean (±SD) amastigote nests of six non-consecutive hematoxilin-eosin stained slides, for each mouse, for five mice from each group and time point. Results from a representative experiment out of two experiments are shown. ND, not detected.