TABLE 3.
Mouse group | No. of positive blood cultures/total no. | Endpoint IgG ELISA titer ± SEM using:
|
|
---|---|---|---|
BL206 antigen | B348 antigen | ||
BL206-infected WT | 0/4 | 22,500 ± 3,200 | 19,200 ± 3,695 |
BL206-infected MyD88−/− | 5/5a | 37,120 ± 22,933b | 15,360 ± 5,724 |
B348-infected WT | 0/4 | 2,000 ± 400 | 12,800 ± 5,226 |
B348-infected MyD88−/− | 4/5c | 3,520 ± 1,176d | 16,000 ± 6,072 |
These results were significantly different from WT values (P = 0.0079; Fisher's exact test).
No significant difference from WT values (P = 0.6201; Mann-Whitney test).
These results were significantly different from WT values (P = 0.0476; Fisher's exact test).
No significant difference from WT values (P = 0.6129; Mann-Whitney test).
All skin, heart, and joint cultures were culture positive (data not shown).