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FIG. 4.

FIG. 4.

Expression of cytokine- and cytokine receptor-encoding genes. (A) Mean expression ratio (log2) kinetics of genes encoding cytokines in HMCs in response to A. fumigatus conidia (P ≤ 0.05 for peak change compared to T0). Results for the following genes are shown: IL1β (interleukin-1β), IL10 (interleukin-10), CSF2 (granulocyte-macrophage colony-stimulator factor). (B) Mean expression ratio (log2) kinetics of genes encoding cytokine receptors in HMCs in response to conidia of A. fumigatus (P ≤ 0.05 for peak change compared to T0). Results for the following genes are shown: TRAF1 (tumor necrosis factor receptor-associated factor 1), IRAK2 (interleukin-1 receptor-associated kinase 2), CSF1R (colony-stimulating factor 1 receptor; formerly McDonough feline sarcoma viral [v-fms] oncogene homolog; CD115), and SMAD6 (SMAD; mothers against DPP homolog 6 [Drosophila]).