TABLE 5.
Characterization of genes differentially regulated in S. gordonii 1.1L derived from DD-PCR
| Gene identification (species) | Homologous protein (GenBank accession no.) | e value | Expression in strain 1.1L |
|---|---|---|---|
| abc-nbd (S. pneumoniae)a | ABC transporter ATP-binding protein—unknown substrate (NP_357743) | 9e−89 | Absent |
| accA (S. pneumoniae)a | Acetyl coenzyme A carboxylase carboxyl transferase subunit alpha (NP_357981) | e−124 | Absent |
| gor (S. pneumoniae)a,b | Glutathione reductase (NP_345281) | e−117 | Absent |
| spo768 (S. pneumoniae) | Conserved hypothetical protein (NP_345266) | e−105 | Absent |
| prmA (S. pneumoniae)a | Ribosomal protein methyltransferase (NP_359200) | 2e−83 | Absent |
| ylbN-like (S. gordonii)b | YlbN-like hypothetical protein (AAG32547) | 6e−50 | Absent |
| gtfG (S. gordonii)b | Glucosyltransferase (AAC43483) | e−162 | Absent |
| fruA (S. mutans)a,b | Fructan β-fructosidase precursor (Q03174) | e−172 | Absent |
| proWX (S. pneumoniae)a | ABC transporter membrane-spanning permease—choline transporter (NP_359269) | 2e−60 | Present |
| lacD (S. pneumoniae)a | Tagatose 1,6-diphosphate aldolase (NP_358666) | 2e−97 | Present |
| tnpA (Lactococcus lactis)b | Transposase (CAA63529) | 5e−66 | Present |
a
Homologous nucleotide sequences were also present in the incomplete and unannotated S. gordonii genome database at www.tigr.org.
b
Multiple amplification products corresponding to these genes were identified.