Table 1.
No. of clones with indicated type of demethylation at:
|
|||
---|---|---|---|
Dyad methylation status | CpG8 | CpG10 | CpG12 |
Symmetrically demethylated (demeth. in both strands) | 9 | 22 | 49 |
Hemimethylated (demeth. in only one strand)* | 9 | 18 | 11 |
Hemimethylated as U/M (demeth. only in top strand) | 1 | 18 | 0 |
Hemimethylated as M/U (demeth. only in bottom strand) | 8 | 0 | 11 |
U/M status at CpG10 was seen in five cancers. M/U at CpG8 was seen in five cancers and a CpG12 in four cancers.