Skip to main content
. Author manuscript; available in PMC: 2006 Aug 2.
Published in final edited form as: Nature. 2005 Dec 11;439(7076):589–593. doi: 10.1038/nature04404

Figure 3.

Figure 3

Synaptic integration of newborn DGCs in the adult brain. a–c, Formation of GABAergic synaptic inputs by GFP+ DGCs. Shown in (a) are sample traces of evoked PSCs recorded under whole-cell voltage-clamp (Vm = −65 mV, 5 mM Kyn) before and after the addition of bicuculline (10 μM). Scale bars: 20 pA and 100 ms. Also shown are the percentages of GFP+ DGCs with detectable GABAergic PSCs, mean amplitude of GABAergic PSCs (b), mean frequency and peak amplitude of GABAergic SSCs recorded at 28 dpi (c). Numbers associated with symbols refer to the number of cells examined. Values represent mean ± s.e.m. (* p < 0.01, ANOVA). d–f, Formation of glutamatergic synaptic inputs by GFP+ DGCs. Same as in (a–c), except that the recordings were carried out in the presence of bicuculline (10 μM). Blue lines indicate the addition of CNQX (50 μM). Scale bars: 10 pA and 40 ms.