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. 2006 Apr 1;332(7544):756–761. doi: 10.1136/bmj.38782.575868.7C

Table 2.

Main outcomes at 12 months. Values are numbers (percentages) of nursing home residents unless stated otherwise

Outcome Control homes (n=6; 170 residents) Intervention homes (n=6; 176 residents) Weighted mean difference (95% CI)* P value* Intracluster correlation coefficient
Taking neuroleptics 69/164 (42) 40/174 (23) 19.1 (0.5 to 37.7) 0.045 0.10
Mean (SD) median dose in chlorpromazine equivalents (No of patients) 107.1 (15.4) (n=69) 102.1 (23.1) (n=40) 4.9 (−20.0 to 29.9) 0.67 0
Taking other psychotropics 92/162 (57) 109/174 (63) −5.9 (−27.2 to 5.5) 0.56 0.080
At least one fall in past 12 months 90/165 (55) 91/175 (52) 2.6 (−18.7 to 23.8) 0.27 0.061
Mean (SD) Cohen-Mansfield agitation inventory§ total (No of patients) 42.0 (5.9) (n=162) 41.6 (7.2) (n=172) 0.3 (−8.3 to 8.9) 0.94 0.087
At least one episode of aggression in past 12 months 16/165 (10) 14/173 (8) 1.6 (−12.7 to 15.8) 0.25 0.10
Mean (SD) wellbeing** (No of patients) 0.9 (0.35) (n=153) 1.1 (0.04) (n=149) −0.2 (−0.5 to 0.2) 0.29 0.075
Spending some time (>0%) asleep** 114/153 (75) 110/149 (74) 0.7 (−8.5 to 9.9) 0.87 0
Spending some time (>0%) withdrawn** 71/153 (46) 56/149 (38) 8.8 (−25.2 to 42.8) 0.58 0.22
*

Adjusted for clustering (estimated from weighted t test).

Mean of medians (data skewed, therefore median appropriate as summary statistic for each cluster).

Truncated at zero.

§

Range 29-203; higher scores mean more agitation (scores >40 usually accepted as clinically significant).

Range −5 to 5.

**

Estimated using dementia care mapping.