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RNA binding by full-length human p53 in vitro. Full-length human p53(1–393) (lanes 2,3,5,6) or truncated human p53(1–363) (lanes 8,9,11,12) were incubated with 32P-labeled RNA 1/(MS2)2 (lanes 1–3,7–9) or 1d/(MS2)2 (lanes 4–6,10–12), and reaction mixtures were analyzed by EMSA. The arrow indicates the protein–RNA complex.
