Fig. 2.

Alignment of deduced Caja-DRB amino acid sequences, given in conventional one-letter code. A dash or dot indicates identity with the consensus or deletion of an amino acid, respectively, whereas ∗ indicates that this part of the sequence is unknown. Amino acids or deletions, which are typical for the -DRB1*03 and -DRB*W16 lineages, are shown in yellow or blue, respectively. Consequently, the names of the hybrid genes, -DRB1*0307 and -DRB1*0312, are shown in both blue and yellow. L, leader peptide and first four amino acids of the coding sequence; β₁, β₁ domain; β₂, β₂ domain; TM, transmembrane region; CYT, cytoplasmic tail; 3′UT, 3′ untranslated region.