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. 2006 Apr 3;116(4):953–960. doi: 10.1172/JCI25091

Figure 7. Human early anterior pituitary development.

Figure 7

(A) Sagittal section from head at 50 dpc. Pound symbol indicates oral cavity. (B–D) Brightfield IHC with antibodies to ACTH (B and D) and GR (C) counterstained by toluidine blue. B and C show higher-magnification views of boxed region in A. Arrows show overlapping expression profiles of cytoplasmic ACTH and nuclear GR in adjacent sections. (D) Anterior pituitary at 8 wpc. bs, basosphenoid bone; h, developing hypothalamus; rp, Rathke’s pouch; t, tongue. Scale bars: 500 μm (A), 100 μm (B and C), 200 μm (D).