Figure 5. Morphologic transformation of newly recruited microsphere-laden monocytes to resident macrophages. Panel A shows a typical whole mount from an animal 24 hours after manipulation, illustrating the typical round aspect of these microsphere-containing phagocytes (400×). The morphologic appearance of the microsphere-laden monocytes changed over a 3-day period by transforming into more dendritic stellate resident macrophages (panel B, 400×).